Bioactive Small Molecules
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Filtered Search Results
Selleck Chemical LLC Degarelix acetate P1094-5MG
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Degarelix acetate (ASP-3550 acetate) is a potent and long-acting luteinizing hormone-releasing hormone (LHRH) antagonist
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Selleck Chemical LLC Fragment Library L1600-5MG/WELL
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A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD)
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Selleck Chemical LLC Lysipressin P1015-50MG
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Lysipressin is a hormone used to prevent or control the frequent urination increased thirst and loss of water associated with diabetes insipidus (water diabetes)
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Abcam GSK484, PAD4 inhibitor, 1MG
MW 510 Da, Purity >98%. Potent and reversible inhibitor of PAD4 (Protein Arginine Deiminase 4) (IC₅₀ = 50 nM). Selective for PAD4 over PAD1-3. GSK484 binds at a different site from the amidines, a conformation of the PAD4 active site where part of the site is re-ordered to form a β-hairpin. It blocks the citrullination of PAD4 target proteins in human neutrophils and inhibits the formation of neutrophil extracellular traps in both mouse and human neutrophils.
The product is subject to the following: Abcam Restricted Use Statement
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Selleck Chemical LLC CCK Octapeptide P1032-5MG
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CCK Octapeptide (Sincalide Cholecystokinin Octapeptide CCK-OP CCK-8 SQ 19 844) is a endogenous peptide hormone found in the intestine and brain that stimulates digestion
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Selleck Chemical LLC Abarelix P1142-5MG
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Abarelix (R3827 PPI 149) is a potent gonadotrophin-releasing hormone (GnRH) antagonist used for prostate cancer treatment
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Selleck Chemical LLC CREBtide P1155-5MG
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CREBtide a synthetic 13 amino acid peptide has been reported as a PKA substrate
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Selleck Chemical LLC Saralasin Acetate P1150-5MG
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Saralasin Acetate an octapeptide analog of angiotensin II is a highly specific competitive inhibitor of angiotensin II that is used in the diagnosis of hypertension
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Selleck Chemical LLC NSC2805 E5844-100MG
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NSC2805 is a potent inhibitor of WWP2 ubiquitin ligase with an IC50 of 0 38 M It is used in cancer research for studying WWP2-associated pathways
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Research Products International Corp CHAPSO, 1 G
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Molecular Formula: C32H58N2O8S
Molecular Weight: 630.88
CAS Number: 82473-24-3
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Cayman Chemical SGC0946trIfluoroacetAT sal 5mg
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A DOT1L inhibitor (IC50 = 0.3 nM); selective for DOT1L over a panel of 12 additional protein methyltransferases, DNMT1, and a panel of 29 receptors and ion channels; reduces H3K79me2 levels in MCF-10A breast cancer cells (IC50 = 8.8 nM); selectively reduces the viability of isolated human cord blood cells transformed with an MLL-AF9 fusion oncogene over those transformed with a TLS-ERG fusion oncogene at 1 and 5 µM; adoptive transfer of isolated human CD3+ T cells pre-incubated with SGC0946 (0.5 µM) prevents weight loss, increases survival, and reduces hepatic and colonic lymphocyte infiltration in a xenogeneic mouse model GVHD
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Medchemexpress LLC Phenyl-boronic acid-d5 | 215527-70-1 | MFCD02093711 | 126.96 | C6H2D5BO2 | 5 G
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Phenyl-boronic acid-d5 is the deuterium-labeled analogue of phenylboronic acid used as an isotope reagent in analytical and synthetic chemistry. It is typically used as a mass spectrometry standard, tracer, or building block in cross-coupling reactions.
- Deuterium-labeled reagent for analytical applications.
- Used as an internal standard for mass spectrometry.
- Suitable for isotopic tracing and synthetic chemistry.
- Solid, stable under normal laboratory storage conditions.
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Medchemexpress LLC BMS-37 | 1675202-20-6 | C27H32N2O4 | 100 MG
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BMS-37 is an immune checkpoint inhibitor targeting PD-1/PD-L1, with an IC50 against the PD-L1/PD-1 complex ranging from 18 to 200 nM. It demonstrates unspecific toxicity towards modified Jurkat T cells, with an EC50 between 3 and 6 μM. This compound is applicable for research into PD-L1-induced T-cell exhaustion or as a PD-L1 ligand for PROTAC molecule synthesis.
- Functions as a PD-1/PD-L1 immune checkpoint inhibitor.
- Exhibits IC50 values for the PD-L1/PD-1 complex between 18 and 200 nM.
- Displays unspecific toxicity against modified Jurkat T cells with an EC50 of 3 to 6 μM.
- Can be used for the study of PD-L1-induced exhaustion of T-cells.
- Suitable for use as a PD-L1 ligand in the synthesis of PROTAC molecules.
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Medchemexpress LLC SEMAPHORIN-7A/SEMA7A 10UG
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5000187468 SEMAPHORIN-7A/SEMA7A 10UG
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Medchemexpress LLC ANGIOPOIETIN-2 HUMA 50UG
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5000187472 ANGIOPOIETIN-2 HUMA 50UG
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